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KMID : 1059519980420040411
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Journal of the Korean Chemical Society
1998 Volume.42 No. 4 p.411 ~ p.415
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Antitumor Evaluation of Epigallocatechin Gallate by Colorimetric Methods
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Baek Soon-Ok
Kim Il-Kwang
Baek Seung-Hwa
Han Du-Seok
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Abstract
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In the present study, we were evaluated cytotoxic effects of epigallocatechin gallate in human skin melanoma cells such as HTB-69. The light microscopic study showed morphological changes of the treated cells. Disruptions in cell organelles were determined by calorimetric methods; 3-(4,5-dimethyl thiazol-2-yl)-2,5diphenyl-2H-tetrazolium bromide (MTT) assay, neutral red (NR) assay and sulforhodamine B protein (SRB) assay. These results suggest that epigallocatechin gallate retains a potential antitumor activity.
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